9XJ8
Cryo-EM structure of Hsp90(E47A)-FKBP8 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heat shock protein HSP 90-alpha | polymer | 732 | 84723.7 | 2 | UniProt (P07900) | Homo sapiens (human) | Heat shock 86 kDa,HSP 86,HSP86,Heat shock protein family C member 1,Lipopolysaccharide-associated protein 2,LAP-2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 2 | C (E) | Isoform 2 of Peptidyl-prolyl cis-trans isomerase FKBP8 | polymer | 281 | 30808.5 | 1 | UniProt (Q14318) | Homo sapiens (human) | PPIase FKBP8,38 kDa FK506-binding protein,38 kDa FKBP,FKBP-38,hFKBP38,FK506-binding protein 8,FKBP-8,FKBPR38,Rotamase |
| 3 | D, E (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence modifications
A, B: 1 - 732 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Ala 47 | Glu 47 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 200255.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1014.4 | |
| All* | Total formula weight | 201270.2 |
