9XIO
Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P218, NADPH and dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 610 | 68842.7 | 4 | UniProt (Q07422) | Toxoplasma gondii | DHFR-TS |
| 2 | E, H, K, N (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | F, I, L, O (A, B, C, D) | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid | non-polymer | 360.4 | 4 | Chemie (MMV) PubChem (66563688) | |||
| 4 | G, J, M, P (A, B, C, D) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 4 | Chemie (UMP) PubChem (65063) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 462 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 275370.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5648.0 | |
| All* | Total formula weight | 281018.6 |
