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9XHR

Crystal Structure of Human Cathepsin B with a D-peptide substrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cathepsin Bpolymer25527956.21UniProt (P07858)
Pfam (PF00112)
Homo sapiens (human)APP secretase,APPS,Cathepsin B1
2B
(C)
ACE-DAR-DLY-DTY-DTY-GLY-0QEpolymer7745.31synthetic construct
3C, D
(A, C)
waterwater18.0261Chemie (HOH)
Sequence modifications
A: 0 - 254 (UniProt: P07858)
PDBExternal DatabaseDetails
Ala 115Ser 194engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28701.4
All*Total formula weight28701.4
*Water molecules are not included.

257629

PDB entries from 2026-08-05

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