9XHA

Cryo-EM structure of unnatural-base aptamer AptD2 with DENV2 NS1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	Non-structural protein 1	polymer	370	42042.6	2	UniProt (P29990)	Dengue virus 2 Thailand/16681/84	NS1
2	B (C)	unnatural-base aptamer AptD2	polymer	72	22741.7	1		synthetic construct
3	D, E (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG) PubChem (24139)

Sequence modifications

A, B: 1 - 352 (UniProt: P29990)

PDB	External Database	Details
Ala -1	-	expression tag
Ser 0	-	expression tag
Glu 353	-	expression tag
Asn 354	-	expression tag
Leu 355	-	expression tag
Tyr 356	-	expression tag
Phe 357	-	expression tag
Gln 358	-	expression tag
Gly 359	-	expression tag
Ala 360	-	expression tag
Ala 361	-	expression tag
Ala 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	106826.8
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	107269.2

*Water molecules are not included.