9XH2
Structure of the CX3CL1.44-US28-GqiN18-scFv16 in the E-state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 352 | 41249.9 | 1 | UniProt (P50148) | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 4 | D (D) | Antibody fragment scFv16 | polymer | 256 | 27340.5 | 1 | Mus musculus | ||
| 5 | E (R) | G-protein coupled receptor homolog US28 | polymer | 362 | 42041.1 | 1 | UniProt (P69332) | Human betaherpesvirus 5 | HHRF3 |
| 6 | F (L) | N-terminal fragment of the engineered fractalkine CX3CL1.44 | polymer | 91 | 10072.6 | 1 | Homo sapiens | ||
| 7 | G (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | H (R) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (5997) |
Sequence modifications
A: 1 - 359 (UniProt: P50148)
B: 2 - 340 (UniProt: P62873)
R: 1 - 354 (UniProt: P69332)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | Ala 8 | conflict |
| Thr 3 | Cys 10 | conflict |
| Ala 6 | Glu 13 | conflict |
| Asp 8 | Ala 15 | conflict |
| Ala 10 | Glu 17 | conflict |
| Val 12 | Arg 19 | conflict |
| Glu 13 | Arg 20 | conflict |
| Arg 14 | Ile 21 | conflict |
| Ser 15 | Asn 22 | conflict |
| Lys 16 | Asp 23 | conflict |
| Met 17 | Glu 24 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165864.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 829.9 | |
| All* | Total formula weight | 166694.7 |
