9XGR
crystal structure of STING-CTD complex with small molecule 09-B11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 241 | 27141.6 | 1 | UniProt (Q86WV6) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | (2S,3S)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE | non-polymer | 304.3 | 1 | Chemie (DH2) PubChem (712316) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 4 | E (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 140 - 379 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Met 139 | - | initiating methionine |
| Arg 232 | His 232 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27141.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 27526.0 |
