9XGK
Structure of mammalian RNA polymerase II stalled by Actinomycin D at the N-1 position.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1970 | 217436.1 | 1 | UniProt (G3MZY8) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Bos taurus (domestic cattle) | 3'-5' exoribonuclease,RNA-directed RNA polymerase II subunit RPB1 |
| 2 | B (B) | DNA-directed RNA polymerase II subunit RPB2 | polymer | 1174 | 134041.4 | 1 | UniProt (A5PJW8) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Bos taurus (domestic cattle) | 3'-5' exoribonuclease,RNA-directed RNA polymerase II subunit RPB2 |
| 3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31466.1 | 1 | UniProt (Q3T0Q3) Pfam (PF01193) Pfam (PF01000) | Bos taurus (domestic cattle) | RNA polymerase II subunit 3,RNA polymerase II subunit B3,DNA-directed RNA polymerase II subunit C |
| 4 | D (D) | DNA-directed RNA polymerase II subunit RPB4 | polymer | 142 | 16347.3 | 1 | UniProt (Q1JQ91) Pfam (PF03874) | Bos taurus (domestic cattle) | RNA polymerase II subunit B4,DNA-directed RNA polymerase II subunit D |
| 5 | E (E) | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | polymer | 210 | 24514.2 | 1 | UniProt (Q2T9T3) Pfam (PF03871) Pfam (PF01191) | Bos taurus (domestic cattle) | RNA polymerases I,II,and III subunit ABC1,DNA-directed RNA polymerase II subunit E,RPB5 homolog |
| 6 | F (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14491.0 | 1 | UniProt (F2Z4C9) Pfam (PF01192) | Bos taurus (domestic cattle) | DNA-directed RNA polymerase II subunit F,RPB6 homolog |
| 7 | G (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (Q5E9B8) Pfam (PF03876) Pfam (PF00575) | Bos taurus (domestic cattle) | RNA polymerase II subunit B7,DNA-directed RNA polymerase II subunit G |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (F2Z4H3) Pfam (PF03870) | Bos taurus (domestic cattle) | |
| 9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14507.2 | 1 | UniProt (Q32P73) Pfam (PF02150) Pfam (PF01096) | Bos taurus (domestic cattle) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I |
| 10 | J (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (Q32P78) Pfam (PF01194) | Bos taurus (domestic cattle) | RNA polymerases I,II,and III subunit ABC5,DNA-directed RNA polymerase III subunit L |
| 11 | K (K) | DNA-directed RNA polymerase II subunit RPB11 | polymer | 117 | 13310.3 | 1 | UniProt (Q32P79) Pfam (PF13656) | Bos taurus (domestic cattle) | RNA polymerase II subunit B11,DNA-directed RNA polymerase II subunit J |
| 12 | L (L) | DNA-directed RNA polymerases I, II, and III subunit RPABC4 | polymer | 58 | 7018.2 | 1 | UniProt (Q3ZBC0) Pfam (PF03604) | Bos taurus (domestic cattle) | RNA polymerases I,II,and III subunit ABC4,DNA-directed RNA polymerase II subunit K |
| 13 | M (M) | Actinomycin D | polymer | 11 | 1291.4 | 1 | BIRD (PRD_000001) | synthetic construct | |
| 14 | N (N) | DNA (NTS, non-template strand) | polymer | 48 | 14697.5 | 1 | synthetic construct | ||
| 15 | O (P) | RNA | polymer | 13 | 4100.5 | 1 | synthetic construct | ||
| 16 | P (T) | DNA (TS, template strand) | polymer | 49 | 15082.7 | 1 | synthetic construct | ||
| 17 | Q, R, T, U, V... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 18 | S (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 552435.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 552983.2 |
