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9XC6

Cryo-EM structure of BMS-986187-bound MOR-Gi1 complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35340282.91UniProt (P63097)Oplophorus gracilirostrisAdenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33536841.31UniProt (P62873)Homo sapiens (human)Transducin beta chain 1
3C
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer566260.31UniProt (P59768)Homo sapiens (human)G gamma-I
4D
(R)
Mu-type opioid receptorpolymer28132187.61UniProt (P35372)Homo sapiens (human)Mu-type opioid receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit, M-OR-1,MOR-1,Mu opiate receptor,Mu opioid receptor,MOP,hMOP
5E
(R)
3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2~{H}-xanthene-1,8-dionenon-polymer470.61Chemie (A1D6B)
PubChem (17379334)
6F
(R)
Levomethadonenon-polymer309.41Chemie (A1ESG)
Sequence modifications
A: 2 - 354 (UniProt: P63097)
PDBExternal DatabaseDetails
Asn 47Ser 47conflict
Ala 203Gly 203conflict
Ala 245Glu 245conflict
Ser 326Ala 326conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight115572.0
Non-Polymers*Number of molecules2
Total formula weight780.0
All*Total formula weight116352.1
*Water molecules are not included.

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PDB entries from 2026-07-08

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