9XC4
Crystal structure of PDE5A in complex with icariin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 324 | 37532.3 | 1 | UniProt (O76074) Pfam (PF00233) | Homo sapiens (human) | cGMP-binding cGMP-specific phosphodiesterase,CGB-PDE |
| 2 | B (E) | beta-D-glucopyranose-(1-5)-[alpha-L-rhamnopyranose-(1-6)]3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbutyl)-4H-chromen-4-one | branched | 678.7 | 1 | In PDB | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37532.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 678.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 181.8 | |
| All* | Total formula weight | 38392.8 |
