9XC3
complex of TCR1414_1-TGFbetaR2(-1)-HLA-DR4, a TGFbetaR2(-1)-HLA-DR4,with a TGFbetaR2(-1) specific TCRl414_1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 181 | 21102.9 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B (B) | HLA class II histocompatibility antigen DR beta chain | polymer | 191 | 22362.8 | 1 | UniProt (A0A1V1IGJ9) | Homo sapiens (human) | MHC class II antigen |
| 3 | C (C) | mutant human TGFbetaR2 | polymer | 16 | 1688.0 | 1 | Homo sapiens | ||
| 4 | D (D) | TCR1414_1 alpha | polymer | 208 | 22622.0 | 1 | Homo sapiens | ||
| 5 | E (E) | TCR1414_1 beta | polymer | 243 | 27896.5 | 1 | Homo sapiens | ||
| 6 | F, G, H, I, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | J (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 8 | L, M, N (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) PubChem (8117) | |||
| 9 | O, P, Q, R, S (A, B, C, D, E) | water | water | 18.0 | 642 | Chemie (HOH) |
Sequence modifications
A: 1 - 180 (UniProt: P01903)
B: 1 - 189 (UniProt: A0A1V1IGJ9)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 95672.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 720.8 | |
| All* | Total formula weight | 96393.0 |
