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9XB1

Cryo-EM structure of human V1aR in apo state at a resolution of 2.8 angstrom

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Vasopressin V1a receptorpolymer38643695.12UniProt (P37288)Homo sapiens (human)V1aR,AVPR V1a,Antidiuretic hormone receptor 1a,Vascular/hepatic-type arginine vasopressin receptor
2C, D
(A, B)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
Sequence modifications
A, B: 33 - 418 (UniProt: P37288)
PDBExternal DatabaseDetails
Cys 341Ser 341engineered mutation
Lys 344Asn 344engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight87390.2
Non-Polymers*Number of molecules2
Total formula weight773.3
All*Total formula weight88163.5
*Water molecules are not included.

248636

PDB entries from 2026-02-04

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