9X7C
Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Mivebresib ABBV-075
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Bromodomain-containing protein 2 | polymer | 108 | 12906.1 | 3 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (human) | O27.1.1 |
| 2 | D, E, F (A, B, C) | N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide | non-polymer | 459.5 | 3 | Chemie (8NG) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38718.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1378.4 | |
| All* | Total formula weight | 40096.6 |
