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9X5J

Cryo-EM structure of the human KCNQ2/3 heteromer channel

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(F, E, H, G)
Calmodulin-1polymer14316164.74UniProt (P0DP23)Homo sapiens (human)
2E, F, H
(B, C, A)
Potassium voltage-gated channel subfamily KQT member 3polymer47153968.83UniProt (O43525)Homo sapiens (human)KQT-like 3,Potassium channel subunit alpha KvLQT3,Voltage-gated potassium channel subunit Kv7.3
3G
(D)
Potassium voltage-gated channel subfamily KQT member 2polymer52559185.31UniProt (O43526)Homo sapiens (human)KQT-like 2,Neuroblastoma-specific potassium channel subunit alpha KvLQT2,Voltage-gated potassium channel subunit Kv7.2
4I, J, K, L
(B, A)
POTASSIUM IONnon-polymer39.14Chemie (K)
PubChem (813)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight285750.7
Non-Polymers*Number of molecules4
Total formula weight156.4
All*Total formula weight285907.1
*Water molecules are not included.

254587

PDB entries from 2026-06-03

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