9WY0
Crystal Structure of HIF-PHD2 in complex with compound 3-1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Egl nine homolog 1 | polymer | 224 | 25371.9 | 1 | UniProt (Q9GZT9) | Homo sapiens (human) | Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) PubChem (27284) | |||
| 3 | C (A) | 6-acetamidopyridine-3-carboxylic acid | non-polymer | 180.2 | 1 | Chemie (A1MCC) | |||
| 4 | D (A) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 188 - 403 (UniProt: Q9GZT9)
| PDB | External Database | Details |
|---|---|---|
| Met 180 | - | initiating methionine |
| Ala 181 | - | expression tag |
| His 182 | - | expression tag |
| His 183 | - | expression tag |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25371.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 236.0 | |
| All* | Total formula weight | 25607.9 |
