9WWL

Cryo-EM structure of transcription activation complex with DevR from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, I (A, B, G)	DNA-directed RNA polymerase subunit alpha	polymer	347	37745.3	3	UniProt (P9WGZ1)	Mycobacterium tuberculosis H37Rv	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C (C)	DNA-directed RNA polymerase subunit beta	polymer	1178	130018.8	1	UniProt (P9WGY9)	Mycobacterium tuberculosis H37Rv	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D (D)	DNA-directed RNA polymerase subunit beta'	polymer	1316	146969.0	1	UniProt (P9WGY7)	Mycobacterium tuberculosis H37Rv	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4	E (F)	RNA polymerase sigma factor SigA	polymer	528	57877.2	1	UniProt (P9WGI1)	Mycobacterium tuberculosis H37Rv	Sigma-A
5	F (O)	DNA (124-MER)	polymer	124	38385.4	1		Mycobacterium tuberculosis H37Rv
6	G (P)	DNA (124-MER)	polymer	124	38327.4	1		Mycobacterium tuberculosis H37Rv
7	H (E)	DNA-directed RNA polymerase subunit omega	polymer	110	11851.1	1	UniProt (P9WGY5)	Mycobacterium tuberculosis H37Rv	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
8	J, K (I, J)	DNA-binding transcriptional activator DevR/DosR	polymer	217	23325.0	2	UniProt (P9WMF9)	Mycobacterium tuberculosis H37Rv
9	L, M (D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
10	N (D)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	583314.9
Non-Polymers*	Number of molecules	3
	Total formula weight	155.1
All*	Total formula weight	583470.1

*Water molecules are not included.