9WVF

Crystal structure of HLA-A*11:01 in complex with KRAS G12S 10-mer peptide (VVVGASGVGK)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	HLA class I histocompatibility antigen, A alpha chain	polymer	276	31986.3	4	UniProt (P04439) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	MHC class I antigen,Human leukocyte antigen A,HLA-A
2	B, E, H, K (B, E, H, K)	Beta-2-microglobulin	polymer	100	11879.4	4	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C, F, I, L (C, F, I, L)	VAL-VAL-VAL-GLY-ALA-SER-GLY-VAL-GLY-LYS	polymer	10	873.0	4		Homo sapiens
4	M, N, O, P, Q... (A, B, D, E, G...)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

A, D, G, J: 1 - 275 (UniProt: P04439)

PDB	External Database	Details
Met 0	-	initiating methionine
Tyr 9	Phe 33	variant
Asp 90	Ala 114	variant
Pro 105	Ser 129	variant

B, E, H, K: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	178954.5
All*	Total formula weight	178954.5

*Water molecules are not included.