9WS5

Crystal structure of PAK2 kinase domain containing D368N mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PAK-2p34	polymer	323	36234.9	1	UniProt (Q13177) Pfam (PF00069)	Homo sapiens (human)	Serine/threonine-protein kinase PAK 2,p34,C-t-PAK2
2	B, C (A)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT) PubChem (311)
3	D (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)

Sequence modifications

A: 228 - 524 (UniProt: Q13177)

PDB	External Database	Details
Met 202	-	initiating methionine
Gly 203	-	expression tag
Ser 204	-	expression tag
Ser 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
Ser 212	-	expression tag
Gln 213	-	expression tag
Asp 214	-	expression tag
Leu 215	-	expression tag
Glu 216	-	expression tag
Val 217	-	expression tag
Leu 218	-	expression tag
Phe 219	-	expression tag
Gln 220	-	expression tag
Gly 221	-	expression tag
Pro 222	-	expression tag
His 223	-	expression tag
Met 224	-	expression tag
Ala 225	-	expression tag
Asp 226	-	expression tag
Leu 227	-	expression tag
Asn 368	Asp 368	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36234.9
Non-Polymers*	Number of molecules	3
	Total formula weight	480.3
All*	Total formula weight	36715.2

*Water molecules are not included.