9WQT
Crystal structure of Saccharomyces cerevisiae isoleucyl-tRNA synthetase in complex with reveromycin A and isoleucine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoleucine--tRNA ligase, cytoplasmic | polymer | 990 | 113864.7 | 1 | UniProt (P09436) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Isoleucyl-tRNA synthetase,IleRS |
| 2 | B (A) | ISOLEUCINE | non-polymer | 131.2 | 1 | Chemie (ILE) PubChem (6306) PubChem (76551) PubChem (94206) PubChem (99288) PubChem (5351546) PubChem (10396882) PubChem (11051686) PubChem (17757247) PubChem (791) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid | non-polymer | 660.8 | 1 | Chemie (GVU) PubChem (131810) PubChem (6439382) PubChem (9939559) PubChem (177675591) PubChem (44561406) PubChem (101119867) PubChem (124511203) PubChem (56840987) PubChem (124931563) PubChem (125183522) PubChem (9939560) PubChem (162845435) PubChem (91202491) PubChem (101119866) PubChem (101119868) PubChem (124931562) PubChem (124931564) PubChem (125183523) PubChem (125183524) PubChem (129628447) PubChem (133562767) PubChem (162845433) PubChem (162845434) | |||
| 5 | G (A) | water | water | 18.0 | 608 | Chemie (HOH) |
Sequence modifications
A: 1 - 984 (UniProt: P09436)
| PDB | External Database | Details |
|---|---|---|
| His 985 | - | expression tag |
| His 986 | - | expression tag |
| His 987 | - | expression tag |
| His 988 | - | expression tag |
| His 989 | - | expression tag |
| His 990 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 113864.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 978.2 | |
| All* | Total formula weight | 114842.8 |
