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9WQR

cryo-EM structure of human organic solute transporter in complex with fidaxomicin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(B, D)
Organic solute transporter subunit betapolymer12814361.32UniProt (Q86UW2)Homo sapiens (human)OST-beta,Solute carrier family 51 subunit beta
2B, C
(A, C)
Organic solute transporter subunit alphapolymer34037768.92UniProt (Q86UW1)Homo sapiens (human)OST-alpha,Solute carrier family 51 subunit alpha
3AA, BA, E, F, G...
(C, A)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
PubChem (5997)
4CA, DA, EA, FA, GA...
(C, A)
PALMITIC ACIDnon-polymer256.414Chemie (PLM)
PubChem (985)
5JA, P, Q, U, V...
(C, A)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.16Chemie (POV)
6LA, S
(C, A)
Fidaxomicinnon-polymer1058.02Chemie (FI8)
PubChem (10034073)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight104260.4
Non-Polymers*Number of molecules34
Total formula weight14906.3
All*Total formula weight119166.7
*Water molecules are not included.

254917

PDB entries from 2026-06-10

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