9WPB
Crystal structure of human transthyretin (TTR) with pryazole-based stabilizer
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Transthyretin | polymer | 130 | 14103.8 | 8 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | I, J, K, L (A, D, E, H) | 4-[2-[3,5-bis(chloranyl)-1~{H}-pyrazol-4-yl]ethyl]benzoic acid | non-polymer | 285.1 | 4 | Chemie (A1MB7) | |||
| 3 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 709 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 112830.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1140.5 | |
| All* | Total formula weight | 113970.6 |
