9WP3
The crystal structure of PDE2A complexed with inhibitor 13j
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 340 | 39763.6 | 4 | UniProt (O00408) Pfam (PF00233) | Homo sapiens (human) | Cyclic GMP-stimulated phosphodiesterase,CGS-PDE,cGSPDE |
| 2 | E, H, K, N (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, I, L, O (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, J, M, P (A, B, C, D) | 7-oxidanylidene-~{N}-[(1~{S})-1-[4-(trifluoromethyl)phenyl]propyl]-2,4,5,6-tetrahydropyrazolo[3,4-c]pyridine-3-carboxamide | non-polymer | 366.3 | 4 | Chemie (A1E46) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 159054.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1824.2 | |
| All* | Total formula weight | 160878.7 |
