9WOB

Crystal structure of SARS-Cov main protease in complex with Telaprevir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase nsp5	polymer	306	33876.6	2	UniProt (P0C6X7)	Severe acute respiratory syndrome coronavirus (SARS-CoV)	3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2	C, D (A, B)	(1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide	non-polymer		681.9	2	BIRD (PRD_002448) Chemie (SV6) PubChem (59235547)
3	E, F (A, B)	water	water		18.0	107	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67753.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1363.7
All*	Total formula weight	69117.0

*Water molecules are not included.