9WNT
Crystal structure of SN45 TCR in complex with C14-Gly-Gly-Ser-Ile lipopeptide-bound Mamu-B*05104
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | MHC class I antigen | polymer | 276 | 31919.1 | 2 | UniProt (B2ZHY7) | Macaca mulatta (Rhesus monkey) | Major histocompatibility complex class I,MHC-class I protein |
| 2 | B, G (B, G) | Beta-2-microglobulin | polymer | 100 | 11731.2 | 2 | UniProt (Q6V7J5) Pfam (PF07654) | Macaca mulatta (Rhesus monkey) | |
| 3 | C, H (C, H) | 4-mer Lipopeptide | polymer | 4 | 332.4 | 2 | synthetic construct | ||
| 4 | D, I (D, I) | SN45 T cell receptor alpha chain | polymer | 197 | 21752.3 | 2 | Macaca mulatta (Rhesus monkey) | ||
| 5 | E, J (E, J) | SN45 T cell receptor beta chain | polymer | 245 | 28086.6 | 2 | Macaca mulatta (Rhesus monkey) | ||
| 6 | AA, BA, CA, DA, FA... (E, F, G, I, A...) | IODIDE ION | non-polymer | 126.9 | 18 | Chemie (IOD) PubChem (30165) | |||
| 7 | EA, M, MA, N, O... (F, A, I, J, B...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
| 8 | GA, LA, S (G, I, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) | |||
| 9 | HA, W (H, C) | MYRISTIC ACID | non-polymer | 228.4 | 2 | Chemie (MYR) PubChem (11005) | |||
| 10 | AB, UA, VA, WA, XA... (J, A, B, E, F...) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 276 (UniProt: B2ZHY7)
| PDB | External Database | Details |
|---|---|---|
| Glu 128 | Arg 149 | conflict |
| Glu 177 | Lys 198 | conflict |
| Glu 223 | Asp 244 | conflict |
| Glu 264 | Lys 285 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 187643.1 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 3616.9 | |
| All* | Total formula weight | 191260.0 |
