9WNJ
[M322I] Menin complexed with KO-539
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Menin | polymer | 488 | 54705.0 | 2 | UniProt (O00255) Pfam (PF05053) | Homo sapiens (human) | |
| 2 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | E, G (A, B) | Ziftomenib | non-polymer | 717.9 | 2 | Chemie (K5O) PubChem (138497449) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 457 (UniProt: O00255)
A, B: 458 - 489 (UniProt: O00255)
| PDB | External Database | Details |
|---|---|---|
| Thr 5 | Ala 5 | engineered mutation |
| Ile 322 | Met 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109410.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1608.5 | |
| All* | Total formula weight | 111018.5 |
