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9WIC

Crystal structure of the human dihydroorotase domain complexed with 5-aminoorotic acid reveals the loop in binding mode

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CAD proteinpolymer39142761.81UniProt (P27708)
Pfam (PF01979)
Homo sapiens (human)
2B
(A)
5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acidnon-polymer171.11Chemie (IJZ)
PubChem (73018)
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
PubChem (32051)
4E
(A)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42761.8
Non-Polymers*Number of molecules3
Total formula weight301.9
All*Total formula weight43063.8
*Water molecules are not included.

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PDB entries from 2026-08-19

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