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9WIC

Crystal structure of the human dihydroorotase domain complexed with 5-aminoorotic acid reveals the loop in binding mode

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CAD proteinpolymer39142761.81UniProt (P27708)Homo sapiens (human)
2B
(A)
5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acidnon-polymer171.11Chemie (IJZ)
PubChem (73018)
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
PubChem (32051)
4E
(A)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42761.8
Non-Polymers*Number of molecules3
Total formula weight301.9
All*Total formula weight43063.8
*Water molecules are not included.

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PDB entries from 2026-07-08

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