9WDW

Cryo-EM structure of helicase DruE in the Druantia anti-phage system elucidates its anti-phage mechanism

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Helicase	polymer	1970	221376.2	2	UniProt (Q4KCB1)	Pseudomonas protegens Pf-5
2	C (C)	DNA (70-MER)	polymer	70	21490.7	1		synthetic construct
3	D, E, F, G, I... (A, B)	ZINC ION	non-polymer		65.4	8	Chemie (ZN) PubChem (32051)
4	H (B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)

Sequence modifications

A, B: 1 - 1948 (UniProt: Q4KCB1)

PDB	External Database	Details
Met -13	-	initiating methionine
Gly -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag
Trp 1949	-	expression tag
Ser 1950	-	expression tag
His 1951	-	expression tag
Pro 1952	-	expression tag
Gln 1953	-	expression tag
Phe 1954	-	expression tag
Glu 1955	-	expression tag
Lys 1956	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	464243.1
Non-Polymers*	Number of molecules	9
	Total formula weight	1029.5
All*	Total formula weight	465272.5

*Water molecules are not included.