9WD8
structure of human KCNQ1-KCNE3-CaM complex with two PIP2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D, E (B, E, H, K) | Calmodulin-1 | polymer | 149 | 16852.5 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 2 | B, J, K, L (C, F, I, L) | Potassium voltage-gated channel subfamily E member 3 | polymer | 106 | 12013.7 | 4 | UniProt (Q9Y6H6) Pfam (PF02060) | Homo sapiens (human) | MinK-related peptide 2,MiRP2,Minimum potassium ion channel-related peptide 2,Potassium channel subunit beta MiRP2 |
| 3 | F, G, H, I (A, D, G, J) | Potassium voltage-gated channel subfamily KQT member 1 | polymer | 546 | 62086.3 | 4 | UniProt (P51787) Pfam (PF00520) Pfam (PF03520) | Homo sapiens (human) | IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1,KQT-like 1,Voltage-gated potassium channel subunit Kv7.1 |
| 4 | M, N, P, Q, R... (B, E, H, K) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | AA, BA, O, V, W... (I, L, C, A, D...) | (2R)-3-{[(S)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl di[(9Z)-octadec-9-enoate] | non-polymer | 1023.1 | 8 | Chemie (A1BBG) |
Sequence modifications
C, F, I, L: 1 - 103 (UniProt: Q9Y6H6)
A, D, G, J: 76 - 620 (UniProt: P51787)
| PDB | External Database | Details |
|---|---|---|
| Ser 104 | - | expression tag |
| Asn 105 | - | expression tag |
| Ser 106 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 75 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 363809.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8505.2 | |
| All* | Total formula weight | 372315.1 |
