9WCF
Cryo-EM structure of hACE2 in complex with NeoCoV RBD_MU3 and antibodies F9-63 and F9-64
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Processed angiotensin-converting enzyme 2 | polymer | 597 | 69153.7 | 1 | UniProt (Q9BYF1) | Homo sapiens (human) | |
| 2 | B (B) | Spike glycoprotein | polymer | 188 | 21306.0 | 1 | UniProt (U5NJG5) | Coronavirus Neoromicia/PML-PHE1/RSA/2011 | S glycoprotein,E2,Peplomer protein |
| 3 | C (C) | F9-63 heavy chain | polymer | 119 | 13237.8 | 1 | Mus musculus | ||
| 4 | D (D) | F9-63 light chain | polymer | 106 | 11482.6 | 1 | Mus musculus | ||
| 5 | E (E) | F9-64 heavy chain | polymer | 117 | 12945.4 | 1 | Mus musculus | ||
| 6 | F (F) | F9-64 light chain | polymer | 106 | 11764.9 | 1 | Mus musculus | ||
| 7 | G (G) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB | |||
| 8 | H, I (H, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB | |||
| 9 | J, K, L, M (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) PubChem (24139) |
Sequence modifications
B: 386 - 573 (UniProt: U5NJG5)
| PDB | External Database | Details |
|---|---|---|
| Ala 431 | Ile 431 | conflict |
| Arg 506 | Asn 506 | conflict |
| Phe 510 | Thr 510 | conflict |
| Arg 547 | Val 547 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 139890.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2246.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 143021.3 |
