9WB2
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Compound No.33 and GRIP Peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, A) | Estrogen receptor | polymer | 254 | 28696.7 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | B, D (D, C) | GRIP Peptide | polymer | 8 | 965.2 | 2 | Homo sapiens | ||
| 3 | E, I (B, A) | 4-[(4-hydroxyphenyl)-phenyl-amino]phenol | non-polymer | 277.3 | 2 | Chemie (A1EVS) | |||
| 4 | F (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 5 | G, H, J (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | K, L, M (B, D, A) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
B, A: 305 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Ala 301 | - | expression tag |
| Gly 302 | - | expression tag |
| Ala 303 | - | expression tag |
| Gly 304 | - | expression tag |
| Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59323.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 847.0 | |
| All* | Total formula weight | 60170.8 |
