9W9I

Cryo-EM structure of the kinesin-2 tail domain in complex with KAP3 and APC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kinesin-like protein KIF3A	polymer	178	21084.1	1	UniProt (P28741)	Mus musculus (house mouse)	Microtubule plus end-directed kinesin motor 3A
2	B (B)	Kinesin-like protein KIF3B, N-terminally processed	polymer	220	25440.1	1	UniProt (Q61771)	Mus musculus (house mouse)
3	C (C)	Kinesin-associated protein 3	polymer	693	80224.1	1	UniProt (P70188) Pfam (PF05804)	Mus musculus (house mouse)	KAP-3,KAP3
4	D (D)	Adenomatous polyposis coli protein	polymer	680	75417.6	1	UniProt (Q61315) Pfam (PF18797) Pfam (PF00514) Pfam (PF16629)	Mus musculus (house mouse)	Protein APC,mAPC

Sequence modifications

A: 536 - 701 (UniProt: P28741)

PDB	External Database	Details
Met 524	-	initiating methionine
Gly 525	-	expression tag
Ser 526	-	expression tag
Ser 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
Ser 534	-	expression tag
Gln 535	-	expression tag

B: 529 - 747 (UniProt: Q61771)

PDB	External Database	Details
Met 528	-	initiating methionine

D: 338 - 1010 (UniProt: Q61315)

PDB	External Database	Details
Met 331	-	initiating methionine
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	202166.0
All*	Total formula weight	202166.0

*Water molecules are not included.