9W99

Structure of betaine-bound state of the human betaine/GABA transporter 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GFP,Maltose/maltodextrin-binding periplasmic protein,Sodium- and chloride-dependent betaine transporter	polymer	1291	144419.7	1	UniProt (P0AEX9) UniProt (P48065)	Homo sapiens	MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,BGT-1,Na(+)/Cl(-) betaine/GABA transporter,Solute carrier family 6 member 12
2	B (A)	TRIMETHYL GLYCINE	non-polymer		118.2	1	Chemie (BET) PubChem (248)
3	C, D (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA) PubChem (923)
4	E (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)

Sequence modifications

A: -676 - -378 (PDB: 9W99)
A: -377 - -12 (UniProt: P0AEX9)

PDB	External Database	Details
Val -66	Ala 338	conflict
Gly -11	-	linker
Gly -10	-	linker
Leu -9	-	linker
Glu -8	-	linker
Val -7	-	linker
Leu -6	-	linker
Phe -5	-	linker
Gln -4	-	linker
Gly -3	-	linker
Pro -2	-	linker
Glu -1	-	linker
Phe 0	-	linker

A: 1 - 614 (UniProt: P48065)

PDB	External Database	Details
Arg 10	Cys 10	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	144419.7
Non-Polymers*	Number of molecules	4
	Total formula weight	199.6
All*	Total formula weight	144619.3

*Water molecules are not included.