9W5I
AGO maturation complex (AMC): AGO2-miRNA duplex in complex with Hsp90 beta and co-chaperone p23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heat shock protein HSP 90-beta | polymer | 724 | 83384.3 | 2 | UniProt (P08238) Pfam (PF13589) Pfam (PF00183) | Homo sapiens (human) | HSP 90,Heat shock 84 kDa,HSP 84,HSP84,Heat shock protein family C member 3 |
| 2 | C (C) | Prostaglandin E synthase 3 | polymer | 160 | 18720.4 | 1 | UniProt (Q15185) Pfam (PF04969) | Homo sapiens (human) | Cytosolic prostaglandin E2 synthase,cPGES,Hsp90 co-chaperone,Progesterone receptor complex p23,Telomerase-binding protein p23 |
| 3 | D (D) | Protein argonaute-2 | polymer | 859 | 97350.2 | 1 | UniProt (Q9UKV8) Pfam (PF16486) Pfam (PF08699) Pfam (PF02170) Pfam (PF16488) Pfam (PF16487) Pfam (PF02171) | Homo sapiens (human) | Argonaute2,hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF-2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer |
| 4 | E (E) | RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3') | polymer | 22 | 7118.2 | 1 | Homo sapiens | ||
| 5 | F (F) | RNA (5'-R(P*CP*UP*AP*UP*AP*CP*AP*AP*UP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*UP*CP*U)-3') | polymer | 22 | 6839.0 | 1 | Homo sapiens | ||
| 6 | G, I (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 7 | H, J, K (A, B, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 296796.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1087.3 | |
| All* | Total formula weight | 297883.6 |
