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9W4T

ratTRPV1 bound with antagonist AMG9810

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Maltose/maltodextrin-binding periplasmic protein,Transient receptor potential cation channel subfamily V member 1polymer1252140466.64UniProt (P0AEX9)
UniProt (O35433)
Pfam (PF00023)
Pfam (PF00520)
Escherichia coli K-12MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like
2E, F, H, I
(A, B, C, D)
(~{Z})-3-(4-~{tert}-butylphenyl)-~{N}-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamidenon-polymer337.44Chemie (A1D6W)
3G
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
Sequence modifications
A, B, C, D: -412 - -47 (UniProt: P0AEX9)
PDBExternal DatabaseDetails
Met -413-initiating methionine
Asn -46-linker
Ser -45-linker
Gly -44-linker
Thr -43-linker
Gly -42-linker
Gly -41-linker
Gly -40-linker
Ser -39-linker
Gly -38-linker
Asp -37-linker
Asp -36-linker
Asp -35-linker
Asp -34-linker
Lys -33-linker
Ser -32-linker
Pro -31-linker
Met -30-linker
Gly -29-linker
Ser -28-linker
His -27-linker
His -26-linker
His -25-linker
His -24-linker
His -23-linker
His -22-linker
His -21-linker
His -20-linker
Gly -19-linker
Ser -18-linker
Asp -17-linker
Tyr -16-linker
Asp -15-linker
Ile -14-linker
Pro -13-linker
Thr -12-linker
Thr -11-linker
Glu -10-linker
Asn -9-linker
Leu -8-linker
Tyr -7-linker
Phe -6-linker
Gln -5-linker
Gly -4-linker
Ala -3-linker
Met -2-linker
Asp -1-linker
Pro 0-linker
A, B, C, D: 1 - 838 (UniProt: O35433)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight561866.2
Non-Polymers*Number of molecules5
Total formula weight1372.6
All*Total formula weight563238.9
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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