9W4N

Structure of rat TRPV1 in complex with SB-366791

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transient receptor potential cation channel subfamily V member 1	polymer	878	99514.6	4	UniProt (O35433) Pfam (PF00023) Pfam (PF00520)	Rattus norvegicus (Norway rat)	TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like
2	E, F, G, H (A, B, C, D)	(2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide	non-polymer		287.7	4	Chemie (ZEI)

Sequence modifications

A, B, C, D: 1 - 838 (UniProt: O35433)

PDB	External Database	Details
Asp -39	-	expression tag
Tyr -38	-	expression tag
Lys -37	-	expression tag
Asp -36	-	expression tag
Asp -35	-	expression tag
Asp -34	-	expression tag
Asp -33	-	expression tag
Lys -32	-	expression tag
Trp -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
Pro -28	-	expression tag
Gln -27	-	expression tag
Phe -26	-	expression tag
Glu -25	-	expression tag
Lys -24	-	expression tag
Gly -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Gly -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ala -15	-	expression tag
Trp -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Pro -11	-	expression tag
Gln -10	-	expression tag
Phe -9	-	expression tag
Glu -8	-	expression tag
Lys -7	-	expression tag
Glu -6	-	expression tag
Phe -5	-	expression tag
Lys -4	-	expression tag
Gly -3	-	expression tag
Leu -2	-	expression tag
Val -1	-	expression tag
Asp 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	398058.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1151.0
All*	Total formula weight	399209.5

*Water molecules are not included.