9W3M
The structures of human dihydroorotate dehydrogenase with inhibitor HL-008
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 366 | 39699.3 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (643976) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D (A) | (4R)-2-[[3-cyclobutyloxy-4-(3-methyl-3-oxidanyl-but-1-ynyl)pyridin-2-yl]amino]-4,5,6,7-tetrahydro-1,3-benzothiazol-4-ol | non-polymer | 399.5 | 1 | Chemie (A1EUS) | |||
| 5 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | G (A) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39699.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1204.1 | |
| All* | Total formula weight | 40903.4 |
