9W2O
Crystal Structure of Norovirus 3C-like Protease in Complex with a Broad-spectrum Inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C-like protease | polymer | 188 | 20126.1 | 1 | UniProt (Q83883) | Norovirus (strain Human/NoV/United States/Norwalk/1968/GI) (Hu/NV/NV/1968/US) | 3CLpro,Calicivirin,NS6 |
| 2 | B (A) | N-[(2S)-1-[(2S,3aS,7aS)-2-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]quinoline-2-carboxamide | non-polymer | 641.8 | 1 | Chemie (A1EYZ) | |||
| 3 | C (A) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: Q83883)
| PDB | External Database | Details |
|---|---|---|
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20126.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 641.8 | |
| All* | Total formula weight | 20767.9 |
