9W2L
Crystal structure of FGFR2 with a macrocyclic compound XS9001
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 2 | polymer | 315 | 35991.4 | 2 | UniProt (P21802) Pfam (PF07714) | Homo sapiens (human) | FGFR-2,K-sam,KGFR,Keratinocyte growth factor receptor |
| 2 | C, F (A, B) | XS9001 | non-polymer | 460.5 | 2 | Chemie (A1EVI) | |||
| 3 | D, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 4 | E, H (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A, B: 456 - 768 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Gly 454 | - | expression tag |
| Pro 455 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71982.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1297.3 | |
| All* | Total formula weight | 73280.1 |
