9W0H

S1P3 in complex with cpd-32 and spm242

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sphingosine 1-phosphate receptor 3,Endo-1,4-beta-xylanase	polymer	512	57235.9	1	UniProt (Q99500) UniProt (P09850)	Homo sapiens (Human)	S1P receptor 3,S1P3,Endothelial differentiation G-protein coupled receptor 3,Sphingosine 1-phosphate receptor Edg-3,S1P receptor Edg-3,Xylanase,1,4-beta-D-xylan xylanohydrolase
2	B (A)	5-bromanyl-~{N}-[(1~{R})-1-[(4-chlorophenyl)amino]-2,2,3,3,3-pentakis(fluoranyl)propyl]pyridine-2-carboxamide	non-polymer		458.6	1	Chemie (A1EUH)
3	C (A)	[(2~{R})-2-azanyl-4-[2-chloranyl-4-(3-hydroxyphenyl)sulfanyl-phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate	non-polymer		433.8	1	Chemie (A1EUC)

Sequence modifications

A: 11 - 224 (UniProt: Q99500)

PDB	External Database	Details
Ser 84	Cys 84	engineered mutation
Tyr 137	His 137	engineered mutation

A: 225 - 409 (UniProt: P09850)

PDB	External Database	Details
Phe 235	Asp 39	engineered mutation
Asp 346	Arg 150	engineered mutation

A: 410 - 522 (UniProt: Q99500)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57235.9
Non-Polymers*	Number of molecules	2
	Total formula weight	892.5
All*	Total formula weight	58128.3

*Water molecules are not included.