9VZY

Crystal structure of Mycobacterium tuberculosis Rv2514c-Rv2515c toxin antitoxin system.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	HTH cro/C1-type domain-containing protein	polymer	393	43480.3	3	UniProt (I6XEH5) Pfam (PF01381) Pfam (PF06114)	Mycobacterium tuberculosis H37Rv	VapB52, Antitoxin
2	D, E, F, G, H... (D, E, F, G, H...)	DUF4411 family protein	polymer	162	18257.6	6	UniProt (I6Y0Y0) Pfam (PF14367)	Mycobacterium tuberculosis H37Rv	VapC52, toxin, ribonuclease
3	J, K, L (A, B, C)	ZINC ION	non-polymer		65.4	3	Chemie (ZN) PubChem (32051)
4	M, N (G, H)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
5	O, P, Q, R, S... (A, B, C, D, E...)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 392 (UniProt: I6XEH5)

PDB	External Database	Details
Met 0	-	initiating methionine

D, E, F, G, H, I: 1 - 153 (UniProt: I6Y0Y0)

PDB	External Database	Details
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Ser -2	-	expression tag
Gln -1	-	expression tag
Ala 0	-	expression tag
Val 1	Met 1	conflict

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	239986.2
Non-Polymers*	Number of molecules	5
	Total formula weight	244.8
All*	Total formula weight	240231.0

*Water molecules are not included.