9VZQ
Crystal structure of RORgamma in complex with novel inverse agonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 246 | 28639.2 | 1 | UniProt (P51449) | Homo sapiens (human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 13 | 1500.7 | 1 | UniProt (Q15788) | Homo sapiens (human) | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | C (A) | (25R)-14beta,17beta-spirost-5-en-3beta-ol | non-polymer | 414.6 | 1 | Chemie (YUV) PubChem (99474) | |||
| 4 | D (A) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30139.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.6 | |
| All* | Total formula weight | 30554.5 |
