9VWS
Cryo-EM structure of human serotonin transporter in complex with tesofensine
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent serotonin transporter | polymer | 630 | 70371.3 | 1 | UniProt (P31645) Pfam (PF03491) Pfam (PF00209) | Homo sapiens (human) | SERT,5HT transporter,5HTT,Solute carrier family 6 member 4 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 3 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 4 | E (A) | (1~{R},2~{R},3~{S},5~{S})-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane | non-polymer | 328.3 | 1 | Chemie (A1EA1) PubChem (11370864) | |||
| 5 | F (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (65082) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70371.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 896.4 | |
| All* | Total formula weight | 71267.7 |
