9VWE
Cryo-EM structure of RSV pre-F (strain A2) in complex with Fabs 1A2 and 2D10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K (A, B, C) | Fusion glycoprotein F0,Fibritin | polymer | 570 | 63340.5 | 3 | UniProt (P03420) UniProt (A0A346FJN8) | Respiratory syncytial virus A2 | Phage neck whiskers protein |
| 2 | B, G, L (D, F, G) | 2D10 heavy chain | polymer | 116 | 12605.8 | 3 | Homo sapiens | ||
| 3 | C, H, M (E, I, J) | 2D10 light chain | polymer | 107 | 11510.7 | 3 | Homo sapiens | ||
| 4 | D, I, N (H, K, M) | 1A2 heavy chain | polymer | 128 | 14157.5 | 3 | Homo sapiens | ||
| 5 | E, J, O (L, N, O) | 1A2 light chain | polymer | 113 | 12389.9 | 3 | Homo sapiens |
Sequence modifications
A, B, C: 1 - 513 (UniProt: P03420)
A, B, C: 518 - 544 (UniProt: A0A346FJN8)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Gly 46 | Ser 46 | conflict |
| Ile 67 | Asn 67 | conflict |
| Asp 92 | Glu 92 | conflict |
| Ser 144 | Val 144 | conflict |
| Cys 149 | Ala 149 | conflict |
| Cys 155 | Ser 155 | conflict |
| Phe 190 | Ser 190 | conflict |
| Leu 207 | Val 207 | conflict |
| Pro 215 | Ser 215 | conflict |
| Cys 290 | Ser 290 | conflict |
| Val 379 | Ile 379 | conflict |
| Val 447 | Met 447 | conflict |
| Cys 458 | Tyr 458 | conflict |
| Gln 465 | Lys 465 | conflict |
| Ser 514 | - | linker |
| Ala 515 | - | linker |
| Ile 516 | - | linker |
| Gly 517 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Val 548 | - | expression tag |
| Pro 549 | - | expression tag |
| Arg 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Ser 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| Ser 559 | - | expression tag |
| Ala 560 | - | expression tag |
| Trp 561 | - | expression tag |
| Ser 562 | - | expression tag |
| His 563 | - | expression tag |
| Pro 564 | - | expression tag |
| Gln 565 | - | expression tag |
| Phe 566 | - | expression tag |
| Glu 567 | - | expression tag |
| Lys 568 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 342013.4 | |
| All* | Total formula weight | 342013.4 |
