9VV6

The structure of ITN bound OXGR1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Fusion protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein	polymer	1398	154297.8	1	UniProt (P0ABE7) UniProt (Q96P68) UniProt (P0AEX9)	Escherichia coli	Cytochrome b-562,Alpha-ketoglutarate receptor 1,G-protein coupled receptor 80,G-protein coupled receptor 99,P2Y purinoceptor 15,P2Y15,P2Y-like GPCR,P2Y-like nucleotide receptor,MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP
2	B (C)	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768)	Homo sapiens (human)	G gamma-I
3	C (D)	Fusion protein,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	609	66900.8	1	UniProt (P62873)	Homo sapiens	Transducin beta chain 1
4	D (B)	Gq alpha	polymer	361	41724.4	1		Homo sapiens
5	E (E)	scFv-16	polymer	547	59466.5	1		Mus musculus
6	F (A)	2-methylidenebutanedioic acid	non-polymer		130.1	1	Chemie (ITN) PubChem (811)

Sequence modifications

A: -107 - -3 (UniProt: P0ABE7)

PDB	External Database	Details
Met -141	-	initiating methionine
Asp -140	-	expression tag
Met -139	-	expression tag
Arg -138	-	expression tag
Val -137	-	expression tag
Pro -136	-	expression tag
Ala -135	-	expression tag
Gln -134	-	expression tag
Leu -133	-	expression tag
Leu -132	-	expression tag
Gly -131	-	expression tag
Leu -130	-	expression tag
Leu -129	-	expression tag
Leu -128	-	expression tag
Leu -127	-	expression tag
Trp -126	-	expression tag
Leu -125	-	expression tag
Ser -124	-	expression tag
Gly -123	-	expression tag
Ala -122	-	expression tag
Arg -121	-	expression tag
Cys -120	-	expression tag
Met -119	-	expression tag
Asp -118	-	expression tag
Tyr -117	-	expression tag
Lys -116	-	expression tag
Asp -115	-	expression tag
Asp -114	-	expression tag
Asp -113	-	expression tag
Asp -112	-	expression tag
Lys -111	-	expression tag
Gly -110	-	expression tag
Gly -109	-	expression tag
Ser -108	-	expression tag
Trp -101	Met 29	conflict
Ile -6	His 124	conflict
Leu -2	-	linker
Gly -1	-	linker
Ser 0	-	linker

A: 1 - 337 (UniProt: Q96P68)
A: 338 - 511 (PDB: 9VV6)
A: 512 - 878 (UniProt: P0AEX9)
A: 890 - 1256 (UniProt: P0AEX9)

PDB	External Database	Details
Gly 879	-	linker
Gly 880	-	linker
Gly 881	-	linker
Gly 882	-	linker
Ser 883	-	linker
Gly 884	-	linker
Gly 885	-	linker
Gly 886	-	linker
Gly 887	-	linker
Ser 888	-	linker
Met 889	-	linker

D: -242 - 0 (PDB: 9VV6)
D: 1 - 340 (UniProt: P62873)

PDB	External Database	Details
Gly 341	-	expression tag
Ser 342	-	expression tag
Ser 343	-	expression tag
Gly 344	-	expression tag
Gly 345	-	expression tag
Gly 346	-	expression tag
Gly 347	-	expression tag
Ser 348	-	expression tag
Gly 349	-	expression tag
Gly 350	-	expression tag
Gly 351	-	expression tag
Gly 352	-	expression tag
Ser 353	-	expression tag
Ser 354	-	expression tag
Gly 355	-	expression tag
Val 356	-	expression tag
Ser 357	-	expression tag
Gly 358	-	expression tag
Trp 359	-	expression tag
Arg 360	-	expression tag
Leu 361	-	expression tag
Phe 362	-	expression tag
Lys 363	-	expression tag
Lys 364	-	expression tag
Ile 365	-	expression tag
Ser 366	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	330250.6
Non-Polymers*	Number of molecules	1
	Total formula weight	130.1
All*	Total formula weight	330380.7

*Water molecules are not included.