9VUU
Crystal structure of SADS-CoV main protease (Lys35Val) in complex with 27h
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ORF1ab polyprotein | polymer | 302 | 32511.8 | 2 | UniProt (A0A2P1G738) Pfam (PF05409) | Swine acute diarrhea syndrome coronavirus | 3C-like proteinase Nsp5 |
| 2 | C, D (A, B) | (2~{R})-1-[4,4-bis(fluoranyl)cyclohexyl]carbonyl-4,4-bis(fluoranyl)-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]pyrrolidine-2-carboxamide | non-polymer | 564.6 | 2 | Chemie (OF9) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 302 (UniProt: A0A2P1G738)
| PDB | External Database | Details |
|---|---|---|
| Val 35 | Lys 2977 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65023.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1129.1 | |
| All* | Total formula weight | 66152.8 |
