9VUI
Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex bound to viral protein C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein | polymer | 602 | 66334.4 | 4 | UniProt (P0AEX9) UniProt (P35974) | Escherichia coli K-12 | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Protein P |
| 2 | E (L) | Maltose/maltodextrin-binding periplasmic protein,RNA-directed RNA polymerase L,Strep II and FLAG tag | polymer | 2630 | 297006.9 | 1 | UniProt (P0AEX9) UniProt (P35975) | Escherichia coli K-12 | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Protein L,Large structural protein,Replicase,Transcriptase |
| 3 | F, G (X, Y) | Maltose/maltodextrin-binding periplasmic protein,Protein C,Green fluorescent protein | polymer | 846 | 94418.8 | 2 | UniProt (P0AEX9) UniProt (P35977) UniProt (P42212) | Escherichia coli K-12 | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP |
| 4 | H, I, J (L) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) PubChem (32051) | |||
| 5 | K (L) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -80 - 283 (UniProt: P0AEX9)
A, B, C, D: 304 - 507 (UniProt: P35974)
L: -383 - -20 (UniProt: P0AEX9)
L: 1 - 2183 (UniProt: P35975)
L: 2184 - 2232 (PDB: 9VUI)
X, Y: -383 - -20 (UniProt: P0AEX9)
X, Y: 1 - 186 (UniProt: P35977)
X, Y: 202 - 440 (UniProt: P42212)
| PDB | External Database | Details |
|---|---|---|
| Met -94 | - | initiating methionine |
| Gly -93 | - | expression tag |
| Ser -92 | - | expression tag |
| Ser -91 | - | expression tag |
| His -90 | - | expression tag |
| His -89 | - | expression tag |
| His -88 | - | expression tag |
| His -87 | - | expression tag |
| His -86 | - | expression tag |
| His -85 | - | expression tag |
| Gly -84 | - | expression tag |
| Thr -83 | - | expression tag |
| Lys -82 | - | expression tag |
| Thr -81 | - | expression tag |
| Gly 284 | - | linker |
| Thr 285 | - | linker |
| Asp 286 | - | linker |
| Tyr 287 | - | linker |
| Asp 288 | - | linker |
| Ile 289 | - | linker |
| Pro 290 | - | linker |
| Thr 291 | - | linker |
| Thr 292 | - | linker |
| Leu 293 | - | linker |
| Glu 294 | - | linker |
| Val 295 | - | linker |
| Leu 296 | - | linker |
| Phe 297 | - | linker |
| Gln 298 | - | linker |
| Gly 299 | - | linker |
| Pro 300 | - | linker |
| Leu 301 | - | linker |
| Gly 302 | - | linker |
| Ser 303 | - | linker |
L: -383 - -20 (UniProt: P0AEX9)
| PDB | External Database | Details |
|---|---|---|
| Met -397 | - | initiating methionine |
| Gly -396 | - | expression tag |
| Ser -395 | - | expression tag |
| Ser -394 | - | expression tag |
| His -393 | - | expression tag |
| His -392 | - | expression tag |
| His -391 | - | expression tag |
| His -390 | - | expression tag |
| His -389 | - | expression tag |
| His -388 | - | expression tag |
| Gly -387 | - | expression tag |
| Thr -386 | - | expression tag |
| Lys -385 | - | expression tag |
| Thr -384 | - | expression tag |
| Gly -19 | - | linker |
| Thr -18 | - | linker |
| Asp -17 | - | linker |
| Tyr -16 | - | linker |
| Asp -15 | - | linker |
| Ile -14 | - | linker |
| Pro -13 | - | linker |
| Thr -12 | - | linker |
| Thr -11 | - | linker |
| Leu -10 | - | linker |
| Glu -9 | - | linker |
| Val -8 | - | linker |
| Leu -7 | - | linker |
| Phe -6 | - | linker |
| Gln -5 | - | linker |
| Gly -4 | - | linker |
| Pro -3 | - | linker |
| Leu -2 | - | linker |
| Gly -1 | - | linker |
| Ser 0 | - | linker |
L: 2184 - 2232 (PDB: 9VUI)
X, Y: -383 - -20 (UniProt: P0AEX9)
| PDB | External Database | Details |
|---|---|---|
| Met -397 | - | initiating methionine |
| Gly -396 | - | expression tag |
| Ser -395 | - | expression tag |
| Ser -394 | - | expression tag |
| His -393 | - | expression tag |
| His -392 | - | expression tag |
| His -391 | - | expression tag |
| His -390 | - | expression tag |
| His -389 | - | expression tag |
| His -388 | - | expression tag |
| Gly -387 | - | expression tag |
| Thr -386 | - | expression tag |
| Lys -385 | - | expression tag |
| Thr -384 | - | expression tag |
| Gly -19 | - | linker |
| Thr -18 | - | linker |
| Asp -17 | - | linker |
| Tyr -16 | - | linker |
| Asp -15 | - | linker |
| Ile -14 | - | linker |
| Pro -13 | - | linker |
| Thr -12 | - | linker |
| Thr -11 | - | linker |
| Leu -10 | - | linker |
| Glu -9 | - | linker |
| Val -8 | - | linker |
| Leu -7 | - | linker |
| Phe -6 | - | linker |
| Gln -5 | - | linker |
| Gly -4 | - | linker |
| Pro -3 | - | linker |
| Leu -2 | - | linker |
| Gly -1 | - | linker |
| Ser 0 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 187 | - | linker |
| Arg 188 | - | linker |
| Glu 189 | - | linker |
| Asn 190 | - | linker |
| Leu 191 | - | linker |
| Tyr 192 | - | linker |
| Phe 193 | - | linker |
| Gln 194 | - | linker |
| Gly 195 | - | linker |
| Asn 196 | - | linker |
| Gly 197 | - | linker |
| Ser 198 | - | linker |
| Ser 199 | - | linker |
| Gly 200 | - | linker |
| Ser 201 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Val 203 | - | insertion |
| Leu 266 | Phe 64 | conflict |
| Thr 267 | Ser 65 | conflict |
| Lys 408 | Ala 206 | conflict |
| Leu 433 | His 231 | conflict |
| Asp 441 | - | expression tag |
| Tyr 442 | - | expression tag |
| Lys 443 | - | expression tag |
| Asp 444 | - | expression tag |
| Asp 445 | - | expression tag |
| Asp 446 | - | expression tag |
| Asp 447 | - | expression tag |
| Lys 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 751182.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 751378.3 |
