9VTX
Cryo-EM structure of Congo Red-bound ATTRA97S amyloid fibrils extracted from patient-derived abdominal adipose biopsy tissu
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Transthyretin | polymer | 127 | 13793.4 | 16 | UniProt (P02766) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | Q, R, S, T, U... (C, D, F, H, L...) | sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | non-polymer | 696.7 | 8 | Chemie (CGO) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ser 97 | Ala 117 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 220693.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5573.3 | |
| All* | Total formula weight | 226267.1 |
