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9VT7

The crystal structure of IDH1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isocitrate dehydrogenase [NADP] cytoplasmicpolymer41747049.62UniProt (O75874)
Pfam (PF00180)
Homo sapiens (human)IDH,IDH1,Cytosolic NADP-isocitrate dehydrogenase,IDPc,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase
2C
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3D, E
(A, B)
waterwater18.0563Chemie (HOH)
Sequence modifications
A, B: 1 - 414 (UniProt: O75874)
PDBExternal DatabaseDetails
Ser 415-expression tag
Leu 416-expression tag
Glu 417-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight94099.1
Non-Polymers*Number of molecules1
Total formula weight743.4
All*Total formula weight94842.5
*Water molecules are not included.

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PDB entries from 2026-07-22

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