9VT6
Crystal structure of STING CTD complex with small molecular inhibitor DDO-88109
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 241 | 27141.6 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 3 | C (A) | 3-bromanyl-5-[[4-(pyrrolidin-1-ylmethyl)phenyl]methoxy]-9~{H}-carbazole | non-polymer | 435.4 | 1 | Chemie (A1ETP) | |||
| 4 | D (A) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 140 - 379 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Met 139 | - | initiating methionine |
| Arg 232 | His 232 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27141.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 475.4 | |
| All* | Total formula weight | 27617.1 |
