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9VSR

The DCY1040 and TUG-891-bound structure of TMEM175

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Endosomal/lysosomal proton channel TMEM175polymer50455667.22UniProt (Q9BSA9)
Pfam (PF06736)
Homo sapiens (human)Potassium channel TMEM175,Transmembrane protein 175,hTMEM175
2C, I
(A, B)
3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acidnon-polymer364.42Chemie (YN9)
3D, J
(A, B)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
4E, F
(A)
(2S)-2-butyl-2-cyclohexyl-6,7-bis(fluoranyl)-5-[3-(1H-1,2,3,4-tetrazol-5-yl)propoxy]-3H-inden-1-onenon-polymer432.52Chemie (A1ETE)
5G, H, K
(A, B)
POTASSIUM IONnon-polymer39.13Chemie (K)
6L, M
(A, B)
waterwater18.032Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111334.4
Non-Polymers*Number of molecules9
Total formula weight2484.4
All*Total formula weight113818.9
*Water molecules are not included.

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