9VSO

Crystal structure of Fab bound to the WT1-derived RMF peptide presented by HLA-A*02:01

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (G, I)	Q2L_Fab_heavy chain	polymer	244	26051.3	2		Homo sapiens
2	B, F (J, K)	Q2L_Fab_light chain	polymer	233	25206.1	2		Homo sapiens
3	C, G (A, C)	HLA class I antigen	polymer	282	32814.3	2	UniProt (Q53Z42) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	HLA-A*02:01,HLA class I histocompatibility antigen A alpha chain,MHC class I antigen,Major histocompatibility complex,class I,A
4	D, H (B, D)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
5	I, J (T, M)	Wilms tumor protein	polymer	9	1109.3	2	UniProt (P19544)	Homo sapiens	WT33

Sequence modifications

A, C: 1 - 275 (UniProt: Q53Z42)

PDB	External Database	Details
Met 0	-	initiating methionine
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag

B, D: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	194120.7
All*	Total formula weight	194120.7

*Water molecules are not included.